HISTONES H3 AND H4 REQUIRE THEIR RELEVANT AMINO-TAILS FOR EFFICIENT NUCLEAR IMPORT AND REPLICATION-COUPLED CHROMATIN ASSEMBLY IN VIVO

Histones H3 and H4 require their relevant amino-tails for efficient nuclear import and replication-coupled chromatin assembly in vivo

Abstract Concomitant chromatin assembly and DNA duplication is essential for cell survival and genome integrity, and requires newly synthesized histones.Although the N-terminal domains of newly synthesized H3 and H4 present critical functions, their requirement for replication-coupled chromatin assembly is controversial.Using the unique capability

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A case of portal biliopathy in a young patient with portal cavernoma secondary to neonatal umbilical vein catheterization

Portal biliopathy (PB) refers to biliary obstruction caused by cavernous transformation of the portal vein (CTPV).CTPV occurs most frequently in patients with liver cirrhosis or malignancy.Less common causes include congenital malformations Round Placemats and neonatal umbilical vein cannulation.We present a case of portal biliopathy in a 28-year-o

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Key elements in regulating the public procurement in the defense sector in accordance with Directive 2009/81/EC

Security and defense in the EU are an area of special Books interest, and their policy is considered as being the policy above all policies.In this sense, the segment of public procurement of arms and military equipment is particularly important, and is regulated by Directive 2009/81/EC.The Republic of Serbia has been trying to follow the EU legacy

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An attempt of early detection of poor outcome after whiplash

The main concern with whiplash is that a large proportion of whiplash patients experience disabling symptoms or whiplash associated disorders (WAD) for months if not years following the accident.Therefore, identifying early prognostic factors of WAD development is important as WAD have widespread clinical and economic consequences.In order to tackl

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